Reem Diab; Mohammad Shahidi Dadras; Azadeh Rakhshan; Ali Kaddah; Parsa Heydarifakher; Fahimeh Abdollahimajd
Abstract
Colorectal cancer is a fatal disease that is continuously increasing. Herein, we report a 36-year-old man with a seven-month history of colon adenocarcinoma, who presented with a painless, exophytic, bilateral scrotal mass that resembled lymphangioma in shape. The histopathological examination revealed ...
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Colorectal cancer is a fatal disease that is continuously increasing. Herein, we report a 36-year-old man with a seven-month history of colon adenocarcinoma, who presented with a painless, exophytic, bilateral scrotal mass that resembled lymphangioma in shape. The histopathological examination revealed metastatic adenocarcinoma, which was morphologically compatible with large bowel origin. To the best of our knowledge, cutaneous metastasis mimicking lymphangioma has rarely been described in the literature. Early diagnosis of cutaneous metastasis is very important and can improve the disease prognosis. A cutaneous metastasis should be considered when encountering any new painless exophytic lesions mimicking lymphangioma.
Fahimeh Abdollahimajd; Reem Diab; Hamideh Moravvej; Ayda Bahmanjahromi; Sahar Dadkhahfar; Azadeh Goodarzi; Afsaneh Sadeghzadeh Bazargan; Sayyed Mojtaba Nekooghadam; Mohammad Nikvar; Mohammad Shahidi Dadras
Abstract
Background: Cutaneous manifestations of coronavirus disease 2019 (COVID-19) are not uncommon and can be the presenting sign of the disease. We aimed to investigate the cutaneous manifestations in COVID-19 patients.Methods: This cross-sectional study was performed on COVID-19 patients referred to Shohada-e ...
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Background: Cutaneous manifestations of coronavirus disease 2019 (COVID-19) are not uncommon and can be the presenting sign of the disease. We aimed to investigate the cutaneous manifestations in COVID-19 patients.Methods: This cross-sectional study was performed on COVID-19 patients referred to Shohada-e Tajrish and Modarres hospitals, Tehran, Iran, from January 1, 2021 to March 31, 2021. Patients with cutaneous lesions were included in the study; if needed, patients were visited in person, and a biopsy was taken.Results: Of the 100 COVID-19 patients in this study, with a mean age of 45.53 ± 17.75 years, 37 (37%) were males. The most common cutaneous manifestation was urticaria (21%), followed by maculopapular eruptions (17%), petechiae/purpura (15%), pityriasis rosea-like lesions (15%), erythema multiforme (7%), pernio (6%), Vesicles/pseudovesicles/bullae (5%), and others (24%). Most lesions were erythematosus (87.63%). Legs (40%) were most frequently involved. The most common accompanying symptom was pruritus (52%), followed by burning sensations (18%) and pain (7%). Six patients had mucosal lesions; these lesions were the only mucocutaneous manifestations in three of them. Skin biopsies were taken from 11 patients, revealing epidermal changesin 10 (90.9%), dermal changes in 7 (63.6%), mucin deposition in 1 (9.1%), perivascular lymphocyte infiltration in 10 (90.9%), and neutrophil infiltration in 1 (9.1%).Conclusion: The frequency of skin manifestations was relatively high in this study, with urticaria as the most common cutaneous presentation of COVID-19. Special attention must be paid to the cutaneous lesions of COVID-19.
